Podcast Interview (A Twofer!): "The Dangers of Omega 6 Seed Oils" and "Soybean Oil Retardation"

David Gornoski interviewed me not once, but twice recently. A first for me, both of these made it to radio! His show appears on WHBO and WFLA in Florida.

The first interview was on February 27, 2021, and the topic was a familiar one:

"The Dangers of Omega 6 Seed Oils"

Introductory, clearly, but hopefully interesting even if you're familiar with the topic.

Or here, for video:

On March 3 David asked me back to discuss a recent paper:

"Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice" (Deol et al, 2020)

Which was brought to my attention to back in December:

@TuckerGoodrich ICYMI https://t.co/K4m3rLOmjo

— Annlee Hines (@ralflongwalker) December 8, 2020

We didn't get into some interesting attributes of this study (like what role linoleic acid actually had) because I wanted to draw attention to some of the previous work this group had done (see citations), leading to my all-time favorite industry rag headline:

"GMO-Sourced Soybean Oil Causes Less Obesity than Conventional Oil."

"Less Obesity", so they know it causes obesity.

That discussion is here:

"Tucker Goodrich on Soybean Oil Retardation"

The article that spurred the discussing was the EU Times lift of an RT International story (last two citations below), unfortunately I didn't have time to deflate some of the more hyperbolic claims from those two articles: I tried to just stick with the science, which does largely support the hyperbole.

I was introduced to David by Chris Knobbe, MD, so thanks for the introduction, Chris!

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Deol, P., Evans, J. R., Dhahbi, J., Chellappa, K., Han, D. S., Spindler, S., & Sladek, F. M. (2015). Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver. PloS One, 10(7), e0132672–e0132672. https://doi.org/10.1371/journal.pone.0132672

Deol, Poonamjot, Fahrmann, J., Yang, J., Evans, J. R., Rizo, A., Grapov, D., Salemi, M., Wanichthanarak, K., Fiehn, O., Phinney, B., Hammock, B. D., & Sladek, F. M. (2017). Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice. Scientific Reports, 7(1), 1–13. https://doi.org/10.1038/s41598-017-12624-9

Deol, Poonamjot, Kozlova, E., Valdez, M., Ho, C., Yang, E.-W., Richardson, H., Gonzalez, G., Truong, E., Reid, J., Valdez, J., Deans, J. R., Martinez-Lomeli, J., Evans, J. R., Jiang, T., Sladek, F. M., & Curras-Collazo, M. C. (2020). Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice. Endocrinology. https://doi.org/10.1210/endocr/bqz044

GMO-Sourced Soybean Oil Causes Less Obesity than Conventional Oil. (2017, October 2). GEN - Genetic Engineering and Biotechnology News. https://www.genengnews.com/news/gmo-sourced-soybean-oil-causes-less-obesity-than-conventional-oil/

Soybean Oil Causes Mental Retardation, Autism, Dementia and Alzheimer’s Research Finds. (2020, January 24). [News]. The European Union Times - World News, Breaking News. https://www.eutimes.net/2020/01/soybean-oil-causes-mental-retardation-autism-dementia-and-alzheimers-research-finds/

Would you like brain damage with that? America’s favorite cooking oil causes neurological changes, says animal study. (n.d.). RT International. Retrieved March 3, 2021, from https://www.rt.com/news/479111-soybean-oil-change-mice-brain/