Wednesday, October 31, 2018

"Don’t Think Too Hard About Your Running Form"

Absolutely right.

The most illuminating moment I had concerning running form was when I got lost on a trail run, and had to get back in the dark.

It turned out running in the dark was easier than walking, and the fact that I couldn't see what I was stepping on in my Vibram FiveFingers made it easier, not harder.

I realized my brain was just interfering with my body, like an annoying backseat driver.

One it was forced by blindness to shut up, things went much more smoothly .

Wednesday, October 24, 2018

"New Hope for Diagnosis of Chronic Infections; and Ancestral Health (Paleo) Survey"

Could be really helpful. "...a new startup, Aperiomics, is offering tests that are capable of identifying 37,000 different infectious pathogens..."

Link via Perfect Health Diet

Wednesday, October 17, 2018

Linoleic Acid and Asthma: Therapies

They never actually mention linoleic acid, but they do discuss lipid peroxidation and some of the products thereof, such as malondialdehyde, which are produced from LA.

"While the specific mechanisms underlying asthma have yet to be identified, there is accumulating evidence that oxidative stress from altered GSH/GSSG redox status may play an important role in the modulation and severity of the disorder."

So the molecular mechanism section is quite incomplete.

As such, it's an annoying article, as it is a  missed opportunity from a mechanistic perspective, many of which have been described under other contexts. It also does not discuss the similarities to atherosclerosis, which are pretty obvious when reading this paper.

But the therapeutic approaches are sound, and validate the underlying concept of omega-6 fat involvement in asthma.

"Glutathione Redox Control of Asthma: From Molecular Mechanisms to Therapeutic Opportunities"

Hat tip to Chris Masterjohn.

Thursday, October 11, 2018

"Fitness versus adiposity in cardiovascular disease risk"

"Having a low VO2max increased CVD mortality risk as much or more than traditional risk factors such as diabetes mellitus, high cholesterol levels, hyperension, or current cigarette smoking"

Wow.

Friday, October 5, 2018

"Muscle damage and inflammation biomarkers after two ultra-endurance mountain races..."

About what you'd expect: exercise is hard on the body.

Due to short follow-up, it doesn't look at how quickly these indicators return to normal, as other studies have.

Monday, October 1, 2018

"Barkley Fall Challenge 2018"

Great story! Read the whole thing!

Link via 2sparrows