Friday, September 23, 2022
Monday, September 12, 2022
Thursday, September 8, 2022
Podcast Ep. 6: Dr. Joshua Durham; Family Doc Gets Red-pilled by Seed Oils—with Dr. Brian Kerley
Dr. Durham is a Family Physician in Boise, Idaho; and is my doctor.
I think this is a great podcast. I really do believe that if we are going to fix our diet problem, we're going to do it one anecdote at a time.
Dr. Durham shares his own story of how, a former athlete, he found himself fat and ill at 38 years old.
And we discuss how this has changed his practice of medicine, since he now has his own success story to tell to his patients.
He also shares some of his patient success stories, and the challenges with getting people to fix their diets.
Podcast:
Podcast:
Show notes:
· https://www.saintalphonsus.org/provider/joshua-durham
Dr. Durham: “If you need a family Dr. here in Boise hit me up. I went from 235lbs to keto to carnivore and then finally came across your info. Now at 195 I feel comfortable knowing what I can and can't have and why I was so sick. Felt great on carnivore but can't live that way forever. Thank you for your work.”
“Doctor of Osteopathy vs. Medical Doctor- What are the Differences?”
Dr. Eric Westman
New Atkins for a New You: The Ultimate Diet for Shedding Weight and Feeling Great by Eric C. Westman, Stephen D. Phinney, Jeff S. Volek
· https://amzn.to/3qd9fzy (this link benefits the podcast!)
Dr. Durham: “Good fat/bad fat” I wrote a post about this: “Good Keto vs. Bad Keto”
· http://yelling-stop.blogspot.com/2021/09/good-keto-vs-bad-keto.html
Dr. Durham: “Then I saw your interview with Paul Saladino…”
· “How Seed Oils Destroy Your Mitochondria and Lead To Chronic Disease, with Tucker Goodrich” https://carnivoremd.com/how-seed-oils-destroy-your-mitochondria-and-lead-to-chronic-disease-with-tucker-goodrich/
“…and then I watched Brad Marshall…”
· Brad’s blog is here: https://fireinabottle.net/
Drs. Kerley and Durham compare “elevator pitches” to patients.
Dr. Durham: “I needed 4 pills based on the guidelines, and I was 38 years old.”
Tucker: “Lean-Mass Hyper Responder”:
Norwitz, N. G., Soto-Mota, A., Kaplan, B., Ludwig, D. S., Budoff, M., Kontush,
A., & Feldman, D. (2022). The Lipid Energy Model: Reimagining Lipoprotein
Function in the Context of Carbohydrate-Restricted Diets. Metabolites,
12(5), 460. https://doi.org/10.3390/metabo12050460
Dr. Durham: 40:02 “American College of Cardiology article…”
Astrup, A., Magkos, F., Bier, D. M., Brenna, J. T., de Oliveira Otto, M. C.,
Hill, J. O., King, J. C., Mente, A., Ordovas, J. M., Volek, J. S., Yusuf, S.,
& Krauss, R. M. (2020). Saturated Fats and Health: A Reassessment and
Proposal for Food-based Recommendations: JACC State-of -the-Art Review. Journal
of the American College of Cardiology, 76(7), 844–857. https://doi.org/10.1016/j.jacc.2020.05.077
See Episode 5, in which we interview Tom Brenna, one of the co-authors of that
article: https://www.youtube.com/watch?v=rrQ8q_ctGUQ
Tucker: “The AGEs, same thing—Chris Masterjohn did a great
post years ago looking into it:
Masterjohn, C. (2011, October 7). Where Do Most AGEs Come From? O Glycation,
How Thy Name Hast Deceived Me! | [Blog]. Chris Masterjohn, PhD. https://chrismasterjohnphd.com/blog/2011/10/07/where-do-most-ages-come-from-o
Tucker: “Polyunsaturated fats are about 10x as effective in
producing advanced glycation end products [than glucose]…”
Fu, M.-X., Requena, J. R., Jenkins, A. J., Lyons, T. J., Baynes, J. W., &
Thorpe, S. R. (1996). The Advanced Glycation End Product,
N-(Carboxymethyl)lysine, Is a Product of both Lipid Peroxidation and
Glycoxidation Reactions. Journal of Biological Chemistry, 271(17),
9982–9986. https://doi.org/10.1074/jbc.271.17.9982
Tucker: Lp(a):
· Hazard ratio 16.8: Tsimikas, S., Brilakis, E. S., Miller, E. R., McConnell, J. P., Lennon, R. J., Kornman, K. S., Witztum, J. L., & Berger, P. B. (2005). Oxidized Phospholipids, Lp(a) Lipoprotein, and Coronary Artery Disease. New England Journal of Medicine, 353(1), 46–57. https://doi.org/10.1056/NEJMoa043175
· Hazard ratio 1 in Africa: Paré, G., Çaku, A., McQueen, M., Anand, S. S., Enas, E., Clarke, R., Boffa, M. B., Koschinsky, M., Wang, X., Yusuf, S., & null, null. (2019). Lipoprotein(a) Levels and the Risk of Myocardial Infarction Among 7 Ethnic Groups. Circulation, 139(12), 1472–1482. https://doi.org/10.1161/CIRCULATIONAHA.118.034311
·
2 sure-fire ways to raise Lp(a):
1. Statins: Yeang, C., Hung, M.-Y., Byun, Y.-S., Clopton, P., Yang, X.,
Witztum, J. L., & Tsimikas, S. (2016). Effect of therapeutic interventions
on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a). Journal
of Clinical Lipidology, 10(3), 594–603. https://doi.org/10.1016/j.jacl.2016.01.005
2. Healthy diet: Navab Mohamad, Reddy Srinivasa T., Van Lenten Brian J., &
Fogelman Alan M. (2004). Apparent Paradox of Low-Fat “Healthy” Diets Increasing
Plasma Levels of Oxidized Low-Density Lipoprotein and Lipoprotein(a). Arteriosclerosis,
Thrombosis, and Vascular Biology, 24(3), 392–393. https://doi.org/10.1161/01.ATV.0000118014.49565.fc
· Pork and LDL: Stewart, J. W., Kaplan, M. L., & Beitz, D. C. (2001). Pork with a high content of polyunsaturated fatty acids lowers LDL cholesterol in women. The American Journal of Clinical Nutrition, 74(2), 179–187. https://doi.org/10.1093/ajcn/74.2.179
Treating Lp(a)/OxLDL with antibodies: https://www.oxitopepharma.com/approach
Dr. Kerley: Robb Wolf interview: https://www.youtube.com/watch?v=Lku8kJdHOqY
Wooden breast in chickens:
Soglia, F., Mudalal, S., Babini, E., Di Nunzio, M., Mazzoni, M., Sirri, F.,
Cavani, C., & Petracci, M. (2016). Histology, composition, and quality
traits of chicken Pectoralis major muscle affected by wooden breast
abnormality. Poultry Science, 95(3), 651–659. https://doi.org/10.3382/ps/pev353
“Dr. Mark Cucuzzella – A Doctor’s Perspective On Treating Diabetes” https://robbwolf.com/2016/07/26/episode-329-dr-mark-cucuzzella-a-doctors-perspective-on-treating-diabetes/
Thursday, September 1, 2022
Podcast Ep. 5: Prof. Tom Brenna on Omega-3 and Omega-6 in Human Health—with Dr Brian Kerley
This is a special episode, which Brian and I are very excited for.
Prof. Brenna is a leading researcher on polyunsaturated fats in child nutrition, who has done both animal and human work demonstrating the importance of a low-linoleic, high DHA diet for human health.
In addition to his academic credentials linked below, he also served on the 2015 Dietary Guidelines Advisory Committee, and on the most recent FAO/WHO Expert Panel on Fats and Fatty Acids, so he's had a real impact on the world dietary recommendations. See the show notes below for more background, and the papers we discussed.
I hadn't spoken to Prof. Brenna prior to this interview, although I had listened to a presentation he made for the International Society for the Study of Fats and Lipids (ISSFAL) of which he is a past president, so I knew he was engaging and quotable. He didn't disappoint.
What I was surprised by was how he made many of the same points about the issues with seed oils that I make, unsolicited by me.
It was a great discussion.
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