Tuesday, November 1, 2022

The Bitter Truth About Seed Oils, Inflammation, and Disease—The Genius Life with Max Lugavere


A really fun interview with a guy who has definitely done his homework.

"What you'll learn from this episode:

    • "How 89% of Americans are metabolically unhealthy, and even our pets have a 60% rate of obesity.
    • "What is the Israeli paradox, and why has India developed more metabolic health disorders since more people have switched from ghee to seed oils?
    • "Why seed oils are inflammatory—and how they affect your LDl, including the difference between oxidized LDL and non-oxidized LDL.
    • "What is a VLDL test, and how can this (often uncovered) test help you understand your real risk factor for atherosclerosis?
    • "The false dichotomy of seed oils vs. saturated fat—and the alternative, anti-inflammatory options: extra virgin olive oil and avocado oil.
"And so much more!


We covered a lot of topics, but heart disease was definitely a big one. 

I've already had a request for some of the references behind that discussion, if you are interested in more I suggest reading this post I co-authored over at Zero Acre:

"Seed Oils as a Driver of Heart Disease"

From that article: 

"Highlights

  • "The United States saw a catastrophic rise in heart disease during the mid-20th century most likely related to changes in dietary linoleic acid intake.
  • "Researchers found a significant disparity in the incidence and prevalence of heart disease, with cultures eating pre-industrial diets having extremely low incidence, if any, compared to populations eating industrialized diets.
  • "Before any human trials had been conducted, leading public health organizations assumed that lowering serum cholesterol levels and increasing seed oil consumption would lead to better health outcomes.
  • "In the United States, steadily rising seed oil consumption drove linoleic acid intake up from 2% of calories in the early 1900s to around 8.9-9.4% by 2010.
  • "By the late 20th century, research had revealed that the susceptibility of LDL particles to oxidation was a much better predictor of heart disease than changes in total cholesterol or LDL cholesterol levels.
  • "Numerous human clinical trials demonstrate that, like smoking, increased seed oil consumption increases LDL’s susceptibility to oxidation, posing a major concern when it comes to cardiovascular disease.
  • "Like smoking, seed oil consumption also induces oxidative stress, induces insulin resistance, damages the arterial endothelial wall, and increases oxidized LDL – a common mechanism that causes heart disease."

And if you are wondering, this is the puppy.


1 comment:

  1. Excellent interview, somewhat more in depth on the topic of arteriosclerosis. Only one point escapes me: does excessive linoleic acid get incorporated into the membrane of low density lipoprotein? Or does the LA content of LDL rise? Or both? Does peroxidation of LA start in the membrane and escalate to its content and the ApoB protein? All the best, Gerlach Sven

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