Thursday, March 31, 2011

Linoleic Acid and Depression

Dr. Deans is really on a roll!

"So, back to the 'vegetable oil' theory: a relative imbalance between the consumption of anti-inflammatory omega 3 fatty acids (fish oil) and inflammatory omega 6 fatty acids (vegetable oil, such as corn oil) predisposes us to inflammation. The omega 6 fatty acids are the precursors for many of the nasty, depressing cytokines mentioned above (such as IL-6).

Well, an absolute flurry of research has been done in this area in the last decade or so, because omega 3 fish oils would be a nifty, natural, presumably no or low side effect, and inexpensive treatment for depression, if it worked. Some studies have been disappointing (3)(4). However, the largest study yet does show benefit (equal to a prescription antidepressant) for those who have depression, but not concurrent anxiety, at a daily dose of 150mg DHA and about 1000mg EPA. (DHA and EPA are fish oil omega 3 fatty acids).