Interview: "Ending the Debate Over Seed Oils"—Fundamental Health with Paul Saladino

This is from August 23rd of last year, but I just realized that I forgot to post about it. It's a follow-up to this:

New Interview: "Fundamental Health with Paul Saladino, MD: How Seed Oils Destroy Your Mitochondria and Lead To Chronic Disease

A bunch of people on Twitter had commented on what a great interview the above was, and I agree, so I reached out to Paul about doing a follow-up.

Enjoy!

Paul has a lot of good material and interviews, so do consider subscribing to his podcast. I have.

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Paul's notes on this podcast:

Time Stamps:

0:10:16 Podcast begins

0:12:16 Tucker’s blog post: https://yelling-stop.blogspot.com/2021/06/thoughts-on-of-rats-and-sidney-diet.html

0:14:16 Compounds that reduce overeating

0:17:16 Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity: https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2012.38

0:23:31 Endocannabinoid signal in the gut controls dietary fat intake: https://www.pnas.org/content/108/31/12904

0:29:56 A Neural Circuit for Gut-Induced Reward: https://www.cell.com/cell/fulltext/S0092-8674(18)31110-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867418311103%3Fshowall%3Dtrue

0:35:46 CRP is a marker of oxidized linoleic acid

0:38:32 Dietary linoleic acid intake and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials: https://pubs.rsc.org/en/content/articlelanding/2017/FO/C7FO00433H

0:43:06 Take a pill or just stop eating so many seed oils?

0:45:16 Low‐Density Lipoprotein Cholesterol Corrected for Lipoprotein(a) Cholesterol, Risk Thresholds, and Cardiovascular Events: https://www.ahajournals.org/doi/10.1161/JAHA.119.016318

0:49:46 A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans: https://pubmed.ncbi.nlm.nih.gov/9844997/

0:54:16 HNE – what is it and why is it important?

0:58:36 Where is linoleic acid even found?

1:02:46 The average amount of linoleic acid in the human diet

1:12:06 Why I don’t eat bacon

1:14:46 Just because a study was conducted a long time ago, doesn’t mean it should be ruled out

1:20:31 Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73): https://www.bmj.com/content/353/bmj.i1246

1:27:16 When low LDL can result in a higher risk of cardiovascular disease

1:28:31 Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis: https://www.bmj.com/content/346/bmj.e8707

1:32:16 Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study: https://pubmed.ncbi.nlm.nih.gov/9989963/

1:40:40 The blood test you should consider getting

1:42:55 The idea of “Intralipid”

1:51:00 Tucker’s personal experience with weight loss and dietary changes

2:03:10 Health Characteristics of the Wayuu Indigenous People: https://academic.oup.com/milmed/article/184/7-8/e371/5481850